Transmitter regulation of voltage-dependent K+ channels expressed in Xenopus oocytes.

Voltage-dependent K+ channels (RBK1, RBK2 and RGK5) were co-expressed in Xenopus oocytes with 5-hydroxytryptamine (5-HT2) receptors. K+ currents measured 2-4 days later were inhibited by 5-HT (100 nM-10 microM, 20-30 s application) by up to 90%. The effect of 5-HT was mimicked by intracellular injec...

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Hauptverfasser: Kavanaugh, M P, Christie, M J, Osborne, P B, Busch, A E, Shen, K Z, Wu, Y N, Seeburg, P H, Adelman, J P, North, R A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151331/
https://ncbi.nlm.nih.gov/pubmed/1651707
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