State-dependent barium block of wild-type and inactivation-deficient HERG channels in Xenopus oocytes

1. The effects of Ba(2+) on current resulting from the heterologous expression of the human ether-à-go-go related gene (HERG) (I(HERG)) was studied with two-electrode voltage clamp techniques in Xenopus oocytes. 2. Ba(2+) produced time- and voltage-dependent block of I(HERG). Significant inhibition...

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Main Authors: Weerapura, Manjula, Nattel, Stanley, Courtemanche, Marc, Doern, David, Ethier, Nathalie, Hébert, Terence E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270020/
https://ncbi.nlm.nih.gov/pubmed/10896755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-00265.x
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