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A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes.

1. The human ether à-go-go-related gene (HERG) encodes a K+ channel that is believed to be the basis of the delayed rectified current, IKr, in cardiac muscle. We studied HERG expressed in Xenopus oocytes using a two-electrode and cut-open oocyte clamp technique with [K+]0 of 2 and 98 mM. 2. The time...

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Detalhes bibliográficos
Main Authors: Wang, S, Liu, S, Morales, M J, Strauss, H C, Rasmusson, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159571/
https://ncbi.nlm.nih.gov/pubmed/9234196
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