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Analysis of Sequence Conservation at Nucleotide Resolution

One of the major goals of comparative genomics is to understand the evolutionary history of each nucleotide in the human genome sequence, and the degree to which it is under selective pressure. Ascertainment of selective constraint at nucleotide resolution is particularly important for predicting th...

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Autors principals: Asthana, Saurabh, Roytberg, Mikhail, Stamatoyannopoulos, John, Sunyaev, Shamil
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230682/
https://ncbi.nlm.nih.gov/pubmed/18166073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030254
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