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Evolutionary constraints in conserved nongenic sequences of mammals

Mammalian genomes contain many highly conserved nongenic sequences (CNGs) whose functional significance is poorly understood. Sets of CNGs have previously been identified by selecting the most conserved elements from a chromosome or genome, but in these highly selected samples, conservation may be u...

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Bibliografiske detaljer
Main Authors: Keightley, Peter D., Kryukov, Gregory V., Sunyaev, Shamil, Halligan, Daniel L., Gaffney, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240079/
https://ncbi.nlm.nih.gov/pubmed/16204190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3942005
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