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Evolutionary constraints in conserved nongenic sequences of mammals

Mammalian genomes contain many highly conserved nongenic sequences (CNGs) whose functional significance is poorly understood. Sets of CNGs have previously been identified by selecting the most conserved elements from a chromosome or genome, but in these highly selected samples, conservation may be u...

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Autors principals: Keightley, Peter D., Kryukov, Gregory V., Sunyaev, Shamil, Halligan, Daniel L., Gaffney, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240079/
https://ncbi.nlm.nih.gov/pubmed/16204190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3942005
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