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Patterns of Evolutionary Constraints in Intronic and Intergenic DNA of Drosophila
We develop methods to infer levels of evolutionary constraints in the genome by comparing rates of nucleotide substitution in noncoding DNA with rates predicted from rates of synonymous site evolution in adjacent genes or other putatively neutrally evolving sites, while accounting for differences in...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327102/ https://ncbi.nlm.nih.gov/pubmed/14762063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1329204 |
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