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Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison

Non-coding DNA comprises ∼80% of the euchromatic portion of the Drosophila melanogaster genome. Non-coding sequences are known to contain functionally important elements controlling gene expression, but the proportion of sites that are selectively constrained is still largely unknown. We have compar...

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Detalles Bibliográficos
Main Authors: Halligan, Daniel L., Keightley, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484454/
https://ncbi.nlm.nih.gov/pubmed/16751341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5022906
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