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Comparison of Human Chromosome 21 Conserved Nongenic Sequences (CNGs) With the Mouse and Dog Genomes Shows That Their Selective Constraint Is Independent of Their Genic Environment

The analysis of conservation between the human and mouse genomes resulted in the identification of a large number of conserved nongenic sequences (CNGs). The functional significance of this nongenic conservation remains unknown, however. The availability of the sequence of a third mammalian genome,...

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Detalhes bibliográficos
Main Authors: Dermitzakis, Emmanouil T., Kirkness, Ewen, Schwarz, Scott, Birney, Ewan, Reymond, Alexandre, Antonarakis, Stylianos E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479112/
https://ncbi.nlm.nih.gov/pubmed/15078857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1934904
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