Native Elongating Transcript Sequencing Reveals Human Transcriptional Activity at Nucleotide Resolution

Major features of transcription by human RNA Polymerase II (Pol II) remain poorly defined due to a lack of quantitative approaches for visualizing Pol II progress at nucleotide resolution. We developed a simple and powerful approach for performing native elongating transcript sequencing (NET-seq) in...

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Veröffentlicht in:Cell
Hauptverfasser: Mayer, Andreas, Iulio, Julia di, Maleri, Seth, Eser, Umut, Vierstra, Jeff, Reynolds, Alex, Sandstrom, Richard, Stamatoyannopoulos, John A., Churchman, L. Stirling
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528962/
https://ncbi.nlm.nih.gov/pubmed/25910208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.03.010
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