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Genome-wide profiling of RNA polymerase transcription at nucleotide resolution in human cells with native elongating transcript sequencing
Many features of gene transcription in human cells remain unclear, mainly due to a lack of quantitative approaches to follow genome transcription with nucleotide precision in vivo. Here we present a robust genome-wide approach to study RNA polymerase (Pol) II-mediated transcription in human cells at...
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Vydáno v: | Nat Protoc |
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Hlavní autoři: | , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5326677/ https://ncbi.nlm.nih.gov/pubmed/27010758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.047 |
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