Phase I and pharmacological study of sequential intravenous topotecan and oral etoposide.

We performed a phase I and pharmacological study to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLT) of a cytotoxic regimen of the novel topoisomerase I inhibitor topotecan in combination with the topoisomerase II inhibitor etoposide, and to investigate the clinical phar...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Herben, V. M., ten Bokkel Huinink, W. W., Dubbelman, A. C., Mandjes, I. A., Groot, Y., van Gortel-van Zomeren, D. M., Beijnen, J. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228184/
https://ncbi.nlm.nih.gov/pubmed/9400949
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky