Randomized comparison of etoposide pharmacokinetics after oral etoposide phosphate and oral etoposide.

Etoposide phosphate is a water-soluble prodrug of etoposide. The plasma pharmacokinetics of etoposide following oral administration of etoposide phosphate or oral etoposide were compared. Seventeen patients with solid tumours were enrolled to receive oral etoposide phosphate 125 mg m(-2) on days 1-5...

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Autors principals: de Jong, R. S., Mulder, N. H., Uges, D. R., Kaul, S., Winograd, B., Sleijfer DTh, Groen, H. J., Willemse, P. H., van der Graaf, W. T., de Vries, E. G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223531/
https://ncbi.nlm.nih.gov/pubmed/9184183
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