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Entecavir for Treatment of Hepatitis B Virus Displays No In Vitro Mitochondrial Toxicity or DNA Polymerase Gamma Inhibition

Therapy with nucleoside reverse transcriptase inhibitors (NRTIs) can be associated with mitochondrial toxicity. In vitro studies have been used to predict the predisposition for and characterize the mechanisms causing mitochondrial toxicity. Entecavir (ETV) is an approved deoxyguanosine nucleoside f...

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Detaylı Bibliyografya
Asıl Yazarlar: Mazzucco, Charles E., Hamatake, Robert K., Colonno, Richard J., Tenney, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224751/
https://ncbi.nlm.nih.gov/pubmed/18056280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01122-07
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