In Vitro Inhibition of Hepadnavirus Polymerases by the Triphosphates of BMS-200475 and Lobucavir

The guanosine analogs BMS-200475 and lobucavir have previously been shown to effectively suppress propagation of the human hepatitis B virus (HBV) and woodchuck hepatitis virus (WHV) in 2.2.15 liver cells and in the woodchuck animal model system, respectively. This repression was presumed to occur v...

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Bibliographic Details
Main Authors: Seifer, Maria, Hamatake, Robert K., Colonno, Richard J., Standring, David N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC106023/
https://ncbi.nlm.nih.gov/pubmed/9835515
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