Potent Efficacy of Entecavir (BMS-200475) in a Duck Model of Hepatitis B Virus Replication

The ability of entecavir (ETV) to inhibit Duck hepatitis B virus (DHBV) infection in duck hepatocytes and ducklings was examined using lamivudine (3TC) as a comparator drug. ETV exhibited antiviral activity (50% effective concentration [EC(50)], 0.13 nM) in DHBV-infected duck hepatocytes that was &g...

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Main Authors: Marion, Patricia L., Salazar, Felix H., Winters, Mark A., Colonno, Richard J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC126982/
https://ncbi.nlm.nih.gov/pubmed/11751115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.1.82-88.2002
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