Efficacy of the Carbocyclic 2′-Deoxyguanosine Nucleoside BMS-200475 in the Woodchuck Model of Hepatitis B Virus Infection

Daily oral treatment with the cyclopentyl 2′-deoxyguanosine nucleoside BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduced the level of woodchuck hepatitis virus (WHV) viremia in chronically infected woodchucks as measured by reductions in serum WH...

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Detalhes bibliográficos
Main Authors: Genovesi, E. V., Lamb, L., Medina, I., Taylor, D., Seifer, M., Innaimo, S., Colonno, R. J., Standring, D. N., Clark, J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC106024/
https://ncbi.nlm.nih.gov/pubmed/9835516
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