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Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus.

BMS-200475 is a novel carbocyclic 2'-deoxyguanosine analog found to possess potent and selective anti-hepatitis B virus (anti-HBV) activity. BMS-200475 is distinguished from guanosine by replacement of the natural furanose oxygen on the sugar moiety with an exo carbon-carbon double bond. In the HepG...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Innaimo, S F, Seifer, M, Bisacchi, G S, Standring, D N, Zahler, R, Colonno, R J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1444
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