Efficacy of the Carbocyclic 2′-Deoxyguanosine Nucleoside BMS-200475 in the Woodchuck Model of Hepatitis B Virus Infection

Daily oral treatment with the cyclopentyl 2′-deoxyguanosine nucleoside BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduced the level of woodchuck hepatitis virus (WHV) viremia in chronically infected woodchucks as measured by reductions in serum WH...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Genovesi, E. V., Lamb, L., Medina, I., Taylor, D., Seifer, M., Innaimo, S., Colonno, R. J., Standring, D. N., Clark, J. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3209
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