Potent Efficacy of Entecavir (BMS-200475) in a Duck Model of Hepatitis B Virus Replication

The ability of entecavir (ETV) to inhibit Duck hepatitis B virus (DHBV) infection in duck hepatocytes and ducklings was examined using lamivudine (3TC) as a comparator drug. ETV exhibited antiviral activity (50% effective concentration [EC(50)], 0.13 nM) in DHBV-infected duck hepatocytes that was >1...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Marion, Patricia L., Salazar, Felix H., Winters, Mark A., Colonno, Richard J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.1.82-88.2002
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