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In Vitro Inhibition of Hepadnavirus Polymerases by the Triphosphates of BMS-200475 and Lobucavir

The guanosine analogs BMS-200475 and lobucavir have previously been shown to effectively suppress propagation of the human hepatitis B virus (HBV) and woodchuck hepatitis virus (WHV) in 2.2.15 liver cells and in the woodchuck animal model system, respectively. This repression was presumed to occur v...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Seifer, Maria, Hamatake, Robert K., Colonno, Richard J., Standring, David N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106023/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835515/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3200
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