Inhibition of Hepatitis B Virus Polymerase by Entecavir

Entecavir (ETV; Baraclude) is a novel deoxyguanosine analog with activity against hepatitis B virus (HBV). ETV differs from the other nucleoside/tide reverse transcriptase inhibitors approved for HBV therapy, lamivudine (LVD) and adefovir (ADV), in several ways: ETV is >100-fold more potent again...

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Autores principales: Langley, David R., Walsh, Ann W., Baldick, Carl J., Eggers, Betsy J., Rose, Ronald E., Levine, Steven M., Kapur, A. Jayne, Colonno, Richard J., Tenney, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866160/
https://ncbi.nlm.nih.gov/pubmed/17267485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02395-06
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