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The TLR3 signaling complex forms by cooperative receptor dimerization
Toll-like receptors (TLRs) initiate immune responses by recognizing pathogen-associated molecules, but the molecular basis for recognition is poorly understood. In particular, it is unclear how receptor-ligand interactions lead to the initiation of downstream signaling. Here, we describe the mechani...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224197/ https://ncbi.nlm.nih.gov/pubmed/18172197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710779105 |
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