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The molecular structure of the Toll-like receptor 3 ligand-binding domain

Innate immunity is the first line of defense against invading pathogens. Toll-like receptors (TLRs) act as sentinels of the innate immune system, sensing a variety of ligands from lipopolysaccharide to flagellin to dsRNA through their ligand-binding domain that is composed of leucine-rich repeats (L...

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Detalhes bibliográficos
Main Authors: Bell, Jessica K., Botos, Istvan, Hall, Pamela R., Askins, Janine, Shiloach, Joseph, Segal, David M., Davies, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182468/
https://ncbi.nlm.nih.gov/pubmed/16043704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505077102
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