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The dsRNA binding site of human Toll-like receptor 3

Pathogen recognition by Toll-like receptors (TLRs) initiates innate immune responses that are essential for inhibiting pathogen dissemination and for the development of acquired immunity. The TLRs recognize pathogens with their N-terminal ectodomains (ECD), but the molecular basis for this recogniti...

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Sonraí Bibleagrafaíochta
Main Authors: Bell, Jessica K., Askins, Janine, Hall, Pamela R., Davies, David R., Segal, David M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482657/
https://ncbi.nlm.nih.gov/pubmed/16720699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603245103
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