Dynamic regulation of macrophage polarization via coupled multicellular networks

per Chuang, Yishan, Leonard, Joshua N
Publicat 2013

Computational Design of Antiviral RNA Interference Strategies That Resist Human Immunodeficiency Virus Escape

per Leonard, Joshua N., Schaffer, David V.
Publicat 2005

FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver

per Marcus, Michelle E., Leonard, Joshua N.
Publicat 2013

Stabilization of Exosome-targeting Peptides via Engineered Glycosylation

per Hung, Michelle E., Leonard, Joshua N.
Publicat a J Biol Chem (2015)

A platform for actively loading cargo RNA to elucidate limiting steps in EV-mediated delivery

per Hung, Michelle E., Leonard, Joshua N.
Publicat a J Extracell Vesicles (2016)

Engineering cell-based therapies to interface robustly with host physiology

per Schwarz, Kelly A., Leonard, Joshua N.
Publicat a Adv Drug Deliv Rev (2016)

Regulation of the IL-10-driven macrophage phenotype under incoherent stimuli

per Chuang, Yishan, Knickel, Brianne K., Leonard, Joshua N.
Publicat a Innate Immun (2016)

Contributions of Unique Intracellular Domains to Switchlike Biosensing by Toll-like Receptor 4

per Daringer, Nichole M., Schwarz, Kelly A., Leonard, Joshua N.
Publicat a J Biol Chem (2015)

Macrophages employ quorum licensing to regulate collective activation

per Muldoon, Joseph J., Chuang, Yishan, Bagheri, Neda, Leonard, Joshua N.
Publicat a Nat Commun (2020)

HIV evades RNA interference directed at TAR by a novel compensatory mechanism

per Leonard, Joshua N., Shah, Priya S., Burnett, John C., Schaffer, David V.
Publicat 2008

Therapeutic Applications of Extracellular Vesicles: Clinical Promise and Open Questions

per György, Bence, Hung, Michelle E., Breakefield, Xandra O., Leonard, Joshua N.
Publicat a Annu Rev Pharmacol Toxicol (2014)

Adding energy minimization strategy to peptide-design algorithm enables better search for RNA-binding peptides: redesigned λ N peptide binds boxB RNA

per Xiao, Xingqing, Hung, Michelle E., Leonard, Joshua N., Hall, Carol K.
Publicat a J Comput Chem (2016)

Building with intent: technologies and principles for engineering mammalian cell-based therapies to sense and respond

per Muldoon, Joseph J., Donahue, Patrick S., Dolberg, Taylor B., Leonard, Joshua N.
Publicat a Curr Opin Biomed Eng (2017)

Modular Extracellular Sensor Architecture for Engineering Mammalian Cell-based Devices

per Daringer, Nichole M., Dudek, Rachel M., Schwarz, Kelly A., Leonard, Joshua N.
Publicat 2014

A Systematic Evaluation of Factors Affecting Extracellular Vesicle Uptake by Breast Cancer Cells

per Stranford, Devin M., Hung, Michelle E., Gargus, Emma S., Shah, Ramille N., Leonard, Joshua N.
Publicat a Tissue Eng Part A (2017)

Multiplexing engineered receptors for multiparametric evaluation of environmental ligands

per Hartfield, Rachel M., Schwarz, Kelly A., Muldoon, Joseph J., Bagheri, Neda, Leonard, Joshua N.
Publicat a ACS Synth Biol (2017)

Biology by Design: From Top to Bottom and Back

per Fritz, Brian R., Timmerman, Laura E., Daringer, Nichole M., Leonard, Joshua N., Jewett, Michael C.
Publicat 2010

Spatial and Functional Heterogeneities Shape Collective Behavior of Tumor-Immune Networks

per Wells, Daniel K., Chuang, Yishan, Knapp, Louis M., Brockmann, Dirk, Kath, William L., Leonard, Joshua N.
Publicat a PLoS Comput Biol (2015)

The COMET toolkit for composing customizable genetic programs in mammalian cells

per Donahue, Patrick S., Draut, Joseph W., Muldoon, Joseph J., Edelstein, Hailey I., Bagheri, Neda, Leonard, Joshua N.
Publicat a Nat Commun (2020)

Structural basis of Toll-Like Receptor 3 Signaling with double-stranded RNA

per Liu, Lin, Botos, Istvan, Wang, Yan, Leonard, Joshua N., Shiloach, Joseph, Segal, David M., Davies, David R.
Publicat 2008