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Adding energy minimization strategy to peptide-design algorithm enables better search for RNA-binding peptides: redesigned λ N peptide binds boxB RNA
Our previously-developed peptide-design algorithm was improved by adding an energy minimization strategy which allows the amino acid sidechains to move in a broad configuration space during sequence evolution. In this work, the new algorithm was used to generate a library of 21-mer peptides which co...
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| Publicado en: | J Comput Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314887/ https://ncbi.nlm.nih.gov/pubmed/27487990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24466 |
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