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Acridine-N Peptide Conjugates Display Enhanced Affinity and Specificity to BoxB RNA Targets
Arginine-rich peptides and small-molecule intercalating agents utilize distinct molecular mechanisms for RNA recognition. Here, we combined these distinct binding modules in an effort to create conjugate ligands with enhanced affinity and specificity using the bacteriophage λ N peptide/boxB interact...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901922/ https://ncbi.nlm.nih.gov/pubmed/20527807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100634h |
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