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Betulinic Acid Derivatives That Target gp120 and Inhibit Multiple Genetic Subtypes of Human Immunodeficiency Virus Type 1

Betulinic acid (BA) derivatives can inhibit human immunodeficiency virus type 1 (HIV-1) entry or maturation depending on side chain modifications. While BA derivatives with antimaturation activity have attracted considerable interest, the anti-HIV-1 profile and molecular mechanism of BA derivatives...

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Detalhes bibliográficos
Main Authors: Lai, Weihong, Huang, Li, Ho, Phong, Li, Zhijun, Montefiori, David, Chen, Chin-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223896/
https://ncbi.nlm.nih.gov/pubmed/17954689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00737-07
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