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Dominant TEL1-hy Mutations Compensate for Mec1 Lack of Functions in the DNA Damage Response

Eukaryotic genome integrity is safeguarded by two highly conserved protein kinases that are called ATR and ATM for humans and Mec1 and Tel1 for Saccharomyces cerevisiae. Although they share sequence similarities and substrates, these protein kinases perform different specialized functions. In partic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baldo, Veronica, Testoni, Valentina, Lucchini, Giovanna, Longhese, Maria Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223299/
https://ncbi.nlm.nih.gov/pubmed/17954565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01214-07
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