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Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression

The evolutionarily conserved yeast Mec1 and Tel1 protein kinases, as well as the Mec1-interacting protein Ddc2, are involved in the DNA damage checkpoint response. We show that regulation of Tel1 and Ddc2–Mec1 activities is important to modulate both activation and termination of checkpoint-mediated...

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書誌詳細
主要な著者: Clerici, Michela, Paciotti, Vera, Baldo, Veronica, Romano, Michele, Lucchini, Giovanna, Longhese, Maria Pia
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC125310/
https://ncbi.nlm.nih.gov/pubmed/11707419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6485
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