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Dominant TEL1-hy Mutations Compensate for Mec1 Lack of Functions in the DNA Damage Response

Eukaryotic genome integrity is safeguarded by two highly conserved protein kinases that are called ATR and ATM for humans and Mec1 and Tel1 for Saccharomyces cerevisiae. Although they share sequence similarities and substrates, these protein kinases perform different specialized functions. In partic...

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Detalhes bibliográficos
Main Authors: Baldo, Veronica, Testoni, Valentina, Lucchini, Giovanna, Longhese, Maria Pia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223299/
https://ncbi.nlm.nih.gov/pubmed/17954565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01214-07
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