Characterization of mec1 Kinase-Deficient Mutants and of New Hypomorphic mec1 Alleles Impairing Subsets of the DNA Damage Response Pathway

DNA damage checkpoints lead to the inhibition of cell cycle progression following DNA damage. The Saccharomyces cerevisiae Mec1 checkpoint protein, a phosphatidylinositol kinase-related protein, is required for transient cell cycle arrest in response to DNA damage or DNA replication defects. We show...

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Detalhes bibliográficos
Main Authors: Paciotti, Vera, Clerici, Michela, Scotti, Maddalena, Lucchini, Giovanna, Longhese, Maria Pia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87054/
https://ncbi.nlm.nih.gov/pubmed/11359899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.12.3913-3925.2001
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