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Characterization of mec1 Kinase-Deficient Mutants and of New Hypomorphic mec1 Alleles Impairing Subsets of the DNA Damage Response Pathway

DNA damage checkpoints lead to the inhibition of cell cycle progression following DNA damage. The Saccharomyces cerevisiae Mec1 checkpoint protein, a phosphatidylinositol kinase-related protein, is required for transient cell cycle arrest in response to DNA damage or DNA replication defects. We show...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Paciotti, Vera, Clerici, Michela, Scotti, Maddalena, Lucchini, Giovanna, Longhese, Maria Pia
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359899/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.12.3913-3925.2001
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