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Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast
The accumulation and aggregation of fragments of amyloid precursor protein (APP) are central to the development of Alzheimer's disease. The production of the small fragment C99 is thought to form the rate-limiting step in the APP processing pathway, which can lead to the production of the toxic...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2220045/ https://ncbi.nlm.nih.gov/pubmed/17869211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.07.033 |
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