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Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity

Asymmetrical localization of transcripts coupled with localized translation constitutes an important mechanism widely deployed to regulate gene activity in a spatial manner. The conserved transmembrane protein Crumbs (Crb) is an important regulator of epithelial polarity. However, it remains unclear...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Zhouhua, Wang, Liwei, Hays, Thomas S., Cai, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213619/
https://ncbi.nlm.nih.gov/pubmed/18195099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707007
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