DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila

Both in Drosophila and vertebrate epithelial cells, the establishment of apicobasal polarity requires the apically localized, membrane-associated Par-3–Par-6–aPKC protein complex. In Drosophila, this complex colocalizes with the Crumbs–Stardust (Sdt)–Pals1-associated TJ protein (Patj) complex. Genet...

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Bibliografiske detaljer
Main Authors: Sotillos, Sol, Díaz-Meco, María Teresa, Caminero, Eva, Moscat, Jorge, Campuzano, Sonsoles
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172211/
https://ncbi.nlm.nih.gov/pubmed/15302858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311031
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