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Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity

Asymmetrical localization of transcripts coupled with localized translation constitutes an important mechanism widely deployed to regulate gene activity in a spatial manner. The conserved transmembrane protein Crumbs (Crb) is an important regulator of epithelial polarity. However, it remains unclear...

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Detalhes bibliográficos
Main Authors: Li, Zhouhua, Wang, Liwei, Hays, Thomas S., Cai, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213619/
https://ncbi.nlm.nih.gov/pubmed/18195099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707007
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