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Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary

Inefficient clearance of dead cells or debris by epithelial cells can lead to or exacerbate debilitating conditions such as retinitis pigmentosa, macular degeneration, chronic obstructive pulmonary disease and asthma. Despite the importance of engulfment by epithelial cells, little is known about th...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Meehan, Tracy L., Kleinsorge, Sarah E., Timmons, Allison K., Taylor, Jeffrey D., McCall, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728319/
https://ncbi.nlm.nih.gov/pubmed/26398951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.021998
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