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Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity

Asymmetrical localization of transcripts coupled with localized translation constitutes an important mechanism widely deployed to regulate gene activity in a spatial manner. The conserved transmembrane protein Crumbs (Crb) is an important regulator of epithelial polarity. However, it remains unclear...

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Bibliografische gegevens
Hoofdauteurs: Li, Zhouhua, Wang, Liwei, Hays, Thomas S., Cai, Yu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213619/
https://ncbi.nlm.nih.gov/pubmed/18195099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707007
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