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Modular Design of Cys-loop Ligand-gated Ion Channels: Functional 5-HT(3) and GABA ρ1 Receptors Lacking the Large Cytoplasmic M3M4 Loop
Cys-loop receptor neurotransmitter-gated ion channels are pentameric assemblies of subunits that contain three domains: extracellular, transmembrane, and intracellular. The extracellular domain forms the agonist binding site. The transmembrane domain forms the ion channel. The cytoplasmic domain is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213565/ https://ncbi.nlm.nih.gov/pubmed/18227272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709896 |
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