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Structure of the M2 Transmembrane Segment of GLIC, a Prokaryotic Cys Loop Receptor Homologue from Gloeobacter violaceus, Probed by Substituted Cysteine Accessibility

GLIC is a homopentameric proton-gated, prokaryotic homologue of the Cys loop receptor family of neurotransmitter-gated ion channels. Recently, crystal structures of GLIC hypothesized to represent an open channel state were published. To explore the channel structure in functional GLIC channels, we t...

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Detalhes bibliográficos
Main Authors: Parikh, Rishi B., Bali, Moez, Akabas, Myles H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077611/
https://ncbi.nlm.nih.gov/pubmed/21362624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221895
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