Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the Plasmodium falciparum equilibrative nucleoside transporter PfENT1

Infection with Plasmodium species parasites causes malaria. Plasmodium parasites are purine auxotrophic. They import purines via an equilibrative nucleoside transporter (ENT). In P. falciparum, the most virulent species, the equilibrative nucleoside transporter 1 (PfENT1) represents the primary puri...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Nishtala, Sita Nirupama, Arora, Avish, Reyes, Jorge, Akabas, Myles H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369291/
https://ncbi.nlm.nih.gov/pubmed/30541922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006547
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