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A Role for the β(1)-β(2) Loop in the Gating of 5-HT(3) Receptors

Based on the Torpedo acetylcholine receptor structure, Unwin and colleagues (Miyazawa et al., 2003; Unwin, 2005) hypothesized that the transduction of agonist binding to channel gate opening involves a “pin-into-socket” interaction between αV46 at the tip of the extracellular β(1)-β(2) loop and the...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Reeves, David C., Jansen, Michaela, Bali, Moez, Lemster, Thomas, Akabas, Myles H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725699/
https://ncbi.nlm.nih.gov/pubmed/16221844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1045-05.2005
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