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Highly Restricted T Cell Repertoire Shaped by a Single Major Histocompatibility Complex–Peptide Ligand in the Presence of a Single Rearranged T Cell Receptor β Chain

The T cell repertoire is shaped by positive and negative selection of thymocytes through the interaction of α/β-T cell receptors (TCR) with self-peptides bound to self-major histocompatibility complex (MHC) molecules. However, the involvement of specific TCR-peptide contacts in positive selection re...

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Detalhes bibliográficos
Main Authors: Fukui, Yoshinori, Hashimoto, Osamu, Inayoshi, Ayumi, Gyotoku, Takahiro, Sano, Tetsuro, Koga, Takahiro, Gushima, Toshifumi, Sasazuki, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213398/
https://ncbi.nlm.nih.gov/pubmed/9730891
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