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An orderly inactivation of intracellular retention signals controls surface expression of the T cell antigen receptor
Exit from the endoplasmic reticulum (ER) is an important checkpoint for proper assembly of multimeric plasma membrane receptors. The six subunits of the T cell receptor (TCR; TCRα, TCRβ, CD3γ, CD3δ, CD3ɛ, and CD3ζ) are each endowed with ER retention/retrieval signals, and regulation of its targeting...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213059/ https://ncbi.nlm.nih.gov/pubmed/15728236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041133 |
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