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Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled α-subunits

The nicotinic acetylcholine receptor of skeletal muscle is composed of five subunits that are assembled in a stepwise manner. Quality control mechanisms ensure that only fully assembled receptors reach the cell surface. Here, we show that Rer1, a putative Golgi-ER retrieval receptor, is involved in...

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Detalhes bibliográficos
Main Authors: Valkova, Christina, Albrizio, Marina, Röder, Ira V., Schwake, Michael, Betto, Romeo, Rudolf, Rüdiger, Kaether, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021032/
https://ncbi.nlm.nih.gov/pubmed/21187406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001624108
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