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Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors
CD19-targeting CAR T cells have shown potency in clinical trials targeting B cell leukemia. Although mainly second generation (2G) CARs carrying CD28 or 4-1BB have been investigated in patients, preclinical studies suggest that third generation (3G) CARs with both CD28 and 4-1BB have enhanced capaci...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689545/ https://ncbi.nlm.nih.gov/pubmed/26700307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144787 |
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