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ROLE OF CHIMAERINS, A GROUP OF Rac-SPECIFIC GTPase ACTIVATING PROTEINS, IN T-CELL RECEPTOR SIGNALING
Chimaerins are GTPase-activating proteins that inactivate the GTP-hydrolase Rac1 in a diacylglycerol-dependent manner. To date, the study of chimaerins has been done mostly in neuronal cells. Here, we show that α2- and β2-chimaerin are expressed at different levels in T-cells and that they participa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277368/ https://ncbi.nlm.nih.gov/pubmed/18249095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.12.015 |
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