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Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor.

The regulation and function of beta2-chimaerin, a novel receptor for the phorbol ester tumour promoters and the second messenger DAG (diacylglycerol), is largely unknown. As with PKC (protein kinase C) isoenzymes, phorbol esters bind to beta2-chimaerin with high affinity and promote its subcellular...

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書誌詳細
主要な著者: Caloca, Maria Jose, Wang, HongBin, Kazanietz, Marcelo G
フォーマット: Artigo
言語:Inglês
出版事項: 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223697/
https://ncbi.nlm.nih.gov/pubmed/12877655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030727
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