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Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor.

The regulation and function of beta2-chimaerin, a novel receptor for the phorbol ester tumour promoters and the second messenger DAG (diacylglycerol), is largely unknown. As with PKC (protein kinase C) isoenzymes, phorbol esters bind to beta2-chimaerin with high affinity and promote its subcellular...

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Main Authors: Caloca, Maria Jose, Wang, HongBin, Kazanietz, Marcelo G
Formato: Artigo
Idioma:Inglês
Publicado: 2003
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223697/
https://ncbi.nlm.nih.gov/pubmed/12877655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030727
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